InSiGHT is pleased to announce the launch of the InSiGHT Podcast, a new series dedicated to exploring the latest advances in hereditary gastrointestinal cancer and polyposis research.
The inaugural episode brings together leading experts to discuss emerging evidence and its impact on clinical practice. Hosted by Dr Sonia Kupfer (University of Chicago Medical Center) and Dr Benjamin Zare (St Mark’s Hospital, London), the episode features Dr Maartje Nielsen and Dr Diantha Terlouw (Leiden University Medical Center, the Netherlands).
The discussion centres on the recent Gastroenterology publication: “Prevalence and Consequences of APC Mosaicism in Patients With Colorectal Adenomas.”
During the episode, the panel examined:
🔹 Why APC mosaicism is often missed by routine blood testing
🔹 Which patients should raise suspicion of mosaicism
🔹 The role of tissue-based testing
🔹 Implications for surveillance and patient management
🔹 Family counselling and reproductive considerations
The episode provides valuable insights into how careful analysis of adenoma tissue can uncover answers when conventional germline testing is inconclusive, ultimately supporting more personalised approaches to care.
We invite clinicians, researchers, genetic counsellors, and everyone else interested in hereditary gastrointestinal cancer to listen to this fascinating first episode of the InSiGHT Podcast.
🎧 Watch the episode: InSiGHT Podcast Episode 1